Sam Farmer makes his picks and score predictions for Week 12 of the NFL season, with Patrick Mahomes and the Chiefs winning at home over the Colts.

The NFL playoff picture is coming into focus heading into Week 12 as some AFC powers find themselves outside the top seven. Kansas City (5-5) has lost to each current Wild Card team so far this year and will likely need to go 6-1 or 7-0 to get into the playoffs.

The Carolina Panthers ' Week 17 matchup against the Seattle Seahawks certainly looks tough on paper. Seattle enters at a strong 12-3 record and as the No. 1 seed in the NFC. But the Panthers have beaten the class of the conference twice before here in 2025, and they can certainly do it again.

Even with Jackson, Baltimore has lost three of their past four but beat the Bears 30-16 in Week 8 in Tyler Huntley's only start this season. Because of the uncertainty at quarterback, the total has dropped, and the SportsLine model has the Over hitting 57% of the time.

We’ve seen some surprising shakeups at the wide receiver position this year. Youngsters such as Jaxon Smith-Njigba and George Pickens have broken out and put up monster stats, while established stars at the position,

Ranking the best kickers to start and which to sit in the fantasy football championships during Week 17 of the 2025 NFL season

As I now try to keep this momentum rolling through the holiday slate, injuries are going to make Week 17 a little tricky, as a number of injured quarterbacks are dampening the overall crop of games. In part because of those injuries,